Free triiodothyronine in nonthyroidal illness

Free triiodothyronine concentrations as measured by two one-step radioimmunoassays in nonthyroidal illness.

Comparison of methods for measuring free thyroxin in nonthyroidal illness.

Patients with severe nonthyroidal illness (NTI) often have decreased serum thyroxin (T4) concentrations and sometimes have decreased free T4 (FT4) and increased tumor necrosis factor-alpha (TNF-alpha) concentrations. We evaluated four commercial methods for measuring FT4 [Abbott IMx, Amersham Amerlex MAB, Nichols, and Diagnostic Products Corporation (DPC) RIA] and one method for TNF-alpha in 41...

Nonthyroidal Illness Syndrome:

Low T3 States Nonthyroidal Illness Syndrome With Low Serum T4 Physiologic Interpretations of NTIS Serum Hormone Levels and Tissue Hormone Supplies in NTIS Is There Evidence for Substances in Serum Which Can Affect T4 Binding to Proteins? TSH Levels Thyroid Hormone Turnover T4 Entry Into Cells and Generation of T3 Thyroid Hormone in Tissues Organ Specific Responses In NTIS Are Patients With NTIS...

Nonthyroidal Illness Syndrome in Adult Horses

BACKGROUND This study was performed to determine whether sick horses have thyroid hormone (TH) alterations similar to those observed in nonthyroidal illness syndrome in other species. HYPOTHESIS Horses suffering from systemic diseases have decreased THs and inappropriately low thyroid-stimulating hormone (TSH). ANIMALS Seventy-one clinically normal horses; 380 hospitalized horses. METHODS...

Discrepancies between serum free triiodothyronine and free thyroxin as measured by equilibrium dialysis and analog radioimmunoassay in nonthyroidal illnesses.

We determined free triiodothyronine (FT3) and free thyroxin (FT4) in serum of patients with various nonthyroidal illnesses (NTI), by both commercial analog-type radioimmunoassays (A) and new equilibrium dialysis procedures (D). The mean FT3 was significantly lower in NTI by both techniques, but the decreases were of different magnitudes. The FT3(D):FT3(A) ratio was 1.96, vs 1.11 for healthy con...